Immunohistochemical analysis of the arterial supply and mast cells of the trigeminal ganglion

The aim of this study was to quantify the distribution microvessels and mast cells in all three parts trigeminal ganglion (TG). Statistical analyses were applied investigate possible micromorphological regional differences their density. Five serially sectioned human TGs prepared for CD34 cell tryptase immunostaining. following quantifications performed microscopic fields TG: microvessel density (MVD), (MCD) ganglionic count. CD34-positive not significantly different any observed TG. neurons showed no significant statistical difference There tryptase-positive within TG, but there an abundant presence periganglionic dural subdural tissues, a finding hitherto reported. We can say that is homogenous vascular pattern TG which excludes local predominance pathogenesis neuralgia. Second, more important, peri-trigeminal indicates important role migraine pain confirms degranulation as main therapeutic goal condition.